Grey’s Anatomy’: Then and Now
Looking back at the cast of the ABC medical drama
As Grey’s Anatomy hits its landmark 300th episode, EW looks back at when each of the current cast members made their debut.
Meredith Grey (Ellen Pompeo)
The Grey in Grey’s Anatomy made her debut in the pilot episode.
Alex Karev (Justin Chambers)
An original member of the Fab Five group of interns, Alex first appeared in the pilot.
Miranda Bailey (Chandra Wilson)
Originally known as the Nazi, Bailey appeared in the pilot.
Richard Webber (James Pickens Jr.)
The original chief at then-Seattle Grace, Webber appeared in the pilot.
Owen Hunt (Kevin McKidd)
Originally a love interest for Cristina Yang (Sandra Oh), Owen debuted in the season 5 premiere.